COMPUTATION-BASED VIRTUAL SCREENING FOR DESIGNING NOVEL ANTIMALARIAL DRUGS BY TARGETING FALCIPAIN-III: A STRUCTURE-BASED DRUG DESIGNING APPROACH

Computation-based virtual screening for designing novel antimalarial drugs by targeting falcipain-III: A structure-based drug designing approach

Background & objectives: Cysteine proteases (falcipains), a papain-family of enzymes of Plasmodium falciparum, are responsible for haemoglobin degradation and thus necessary for its survival during asexual life cycle phase inside the human red blood cells while remaining non-functional for the human body.Therefore, these can act as potential target

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Public key searchable encryption scheme based on blockchain

Aiming at the trapdoor security problem of the public key encryption scheme,a random number constructing trapdoor and index was introduced to defend against keyword guessing attacks from the server and avoid data leakage caused by server curious behavior.Research on trusted issues of third parties,the blockchain mechanism with a kiara sky peach san

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